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What is Project CLEAR?

Project CLEAR logoProject CLEAR is a clinical trial led by UC Irvine infectious disease expert Dr. Susan S. Huang.
The study is aimed at preventing infection and hospitalization in patients who have MRSA.

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What is MRSA?

MRSA, or methicillin-resistant Staphylococcus aureus, is a "superbug" that is resistant to common antibiotics. It is found in many places,
including hospitals, nursing homes, gyms and
schools.

Who is eligible for the MRSA trial?

People who:
  • are at least 18 years of age and have been  admitted to a hospital in the previous 30 days or have been discharged to a nursing home
  • have had a positive culture for MRSA during a recent hospitalization or within 30 days of admission or after discharge
  • are able to give consent or have a primary caregiver provide consent
  • are able to bathe or shower regularly or have a primary caregiver perform this task

Why should I participate?

Even if MRSA is not causing an infection, people with MRSA who have recently been hospitalized or who have chronic illnesses are at higher risk of developing MRSA infections in the future. This clinical trial looks at two ways to help prevent future infections.

Is this a trial to treat MRSA?

No. This trial compares methods intended to prevent future infections among people with MRSA. If you have a MRSA infection, you should be seen by a doctor to have your infection treated. However, if you do have an infection, you may still join the trial if you meet the eligibility rules above.

What is being studied?

The clinical trial compares two ways of preventing future infections among people with MRSA:
  • Patients in the education group receive detailed information about MRSA, including home hygiene practices and cleaning tips.
  • Patients in the decolonization group receive special soap and medicine (provided for free) to be used to reduce or eliminate MRSA bacteria from the body. This group also is given detailed information about MRSA.

Can I choose a group?

No, participants are randomly assigned. You will have an equal chance of being in either group.

How long is the study?

We will support and follow you for one year, with telephone calls twice a month. You will be paid to have four follow-up clinic visits.

How much will I be paid?

You will be paid $25 for the first visit (month 1); $30 for the second visit (month 3); $35 for the third visit (month 6); $50 for the fourth visit (month 9), for a total of $140.

For more information about Project CLEAR or to enroll in this clinical trial, please contact our staff toll-free at 1.855.RID.MRSA (1.855.743.6772).